Assistant Professor in Dermatology
Brigham and Women's Hospital
Harvard Skin Disease Research Center
77 Ave Louis Pasteur
Harvard Institutes of Medicine, Rm. 650
Boston, MA 02115
1. Woynarowska B, Dimitroff, C.J, Skrincosky D, Sharma M, Matta K, Bernacki RJ. The effect of a 4-fluoro-glucosamine analog on the adhesion of human colon carcinoma HT-29 cells, Glycoconjugate J., 1996; 13(4):663-674.
2. Dimitroff CJ, Sharma A, Bernacki RJ. Cancer metastasis: a search for therapeutic inhibition (Review), Cancer Invest., 1998; 16(4):279-290, 1998.
3. Dimitroff, C.J., Pera, P., Dall’Olio, F., Matta, K.L., Chandrasekaran, E.V., Lau, J.T. and Bernacki, R.J. Cell surface N-acetylneuraminic acid 2,3-galactoside-dependent intercellular adhesion of human colon cancer cells, Biochem. Biophys. Res. Comm., 256:631-636, 1999.
4. Dimitroff CJ, Klohs W, Sharma A, Pera P, Driscoll D, Veith J, Steinkampf R, Schroeder M, Klutchko S, Sumlin A, Henderson B, Dougherty TJ, Bernacki RJ. Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD166285 and PD173074: implications for combination treatment with photodynamic therapy, Invest. New Drugs, 1999; 17(2):121-135.
5. Sackstein R, Dimitroff CJ. A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity, Blood, 2000; 96: 2765-2774.
6. Dimitroff CJ, Lee J, Fuhlbrigge RC, Sackstein R. A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic progenitor cells. Proc. Natl. Acad. Sci., 2000; 97(25), 13841-13846.
7. Dimitroff CJ, Lee JY, Rafii S, Fuhlbrigge RC, Sackstein R. CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J. Cell Biology, 2001; 153:1277-1286.
8. Dimitroff CJ, Lee JY, Schor K, Sandmaier B, Sackstein R. Differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1. J. Biol. Chem., 2001; 276(50):47623-47631
9. Fuhlbrigge R.C, King S, Dimitroff CJ, Kupper TS, Sackstein R. Direct real-time observation of E-and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on western blots. J. Immunology, 2002; 168:5645-51.
10. Dimitroff CJ, Bernacki RJ, Sackstein R. Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen: Implications in modulating lymphocyte migration to skin. Blood, 2003; 101(2):602-610.
11. Dimitroff CJ, Kupper TS, Sackstein R. Prevention of leukocytic migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen. J. Clin. Invest., 2003; 112, 1008-1018.
12. Dimitroff CJ, Lechpammer M, Long-Woodward, D, Kutok, JL. Rolling of Human Bone-Metastatic Prostate Tumor Cells on Human Bone Marrow Endothelial Cells under Shear Flow is Mediated by E-selectin. Cancer Research, 2004; 64 (15): 5261-5269.
13. Dimitroff CJ, Descheny L, Trujillo N, Kim R, Huang W, Nguyen V, Pienta K, Kutok JL, Rubin MA. Identification of Leukocyte E-selectin Ligands, P-selectin Glycoprotein Ligand-1 and E-selectin Ligand-1, on Human Metastatic Prostate Tumor Cells. Cancer Research, 2005; 65(13):5750-5760.
14. Dimitroff CJ. Sharing of the Same Vascular Addressins for Osteotropic Behavior of Hematopoietic Progenitor Cells and Cancer. BoneKEy-Osteovision., 2005; 2(10):16-19.
15. Descheny L, Gainers ME, Walcheck B, Dimitroff CJ. Ameliorating Skin-Homing Receptors on Malignant T cells with a Fluorosugar Analog of N-acetylglucosamine: P-selectin Ligand is a More Sensitive Target than E-selectin Ligand, J Invest Dermatol. 126(9):2065-73, 2006.
16. Alcaide P, King SL, Dimitroff CJ, Lim Y-C, Fuhlbrigge RC, Luscinskas FW. The 130-kDa glycoform of CD43 is an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo. J. Invest. Derm., 2007; 127(8):1964-72.
17. Barthel SB, Gavino J, Dimitroff CJ. Targeting selectin – selectin ligand interactions in inflammation and cancer. Expert Opin. Ther. Targets, 2007; 11(11):1473-1491.
18. Gainers ME, Descheny L, Barthel SB, ME, Liu L, Wurbel M, Dimitroff CJ. Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis. J. Immunology, 2007;179(12):8509-8518.
19. Yamanaka K, Dimitroff CJ, Fuhlbrigge RC, Kakeda M, Kurokawa I, Mizutani H, Kupper TS. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J. Allergy Clin. Immunol., In press.